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Diabetic retinopathy feature extraction images based on confusion neural network

Mohamed Elageli M. Ghet, Omar Ismael Al-Sanjary, Ali Khatibi

Abstract


The diagnosis of diabetic retinopathy depends on the evaluation of retinal fundus pictures. The current methods have been successful in extracting features from fundus images, but due to the complex blood vessel distribution in these images and the presence of a great deal of noise, simple methods based on threshold segmentation and clustering are vulnerable to feature loss during the extraction process. For example, the small blood vessels in the fundus are lost, and the branches of blood vessels are blurred. In addition, the noise in medical images is mainly distributed in the high-frequency area of the image. The proposed method to segment the retinal fundus vessels in the DRIVE and STARE datasets, the average accuracy of this method is 95.45% and 94.81%, respectively, and the sensitivity and specificity are 73.35%, 75.39% and 97.34%, 95.75%. In addition, compared with related methods, the proposed method has higher segmentation accuracy, and after segmentation, the fundus blood vessels have higher integrity, clear structure, and less loss of small blood vessels.


Keywords


Diabetic Retinopathy; Medical Images; Confusion Neural Network

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References


1. Kumar A, Yaduvanshi RS. Quantum antenna operating at 430 to 750 THz band, inspired through human eye. Journal of Information and Optimization Sciences 2020; 41(6): 1365–1373. doi: 10.1080/02522667.2020.1809093.

2. Goldsmith TH. Optimization, constraint, and history in the evolution of eyes. The Quarterly Review of Biology 1990; 65(3): 281–322. doi: 10.1086/416840.

3. Prakash TD, Rajashekar D, Srinivasa G. Comparison of algorithms for segmentation of blood vessels in fundus images. In: 2016 2nd International Conference on Applied and Theoretical Computing and Communication Technology (iCATccT); 2016 Jul 21–23; Bangalore, India. New York: IEEE; 2017. p. 114–118.

4. Zhou C, Zhang X, Chen H. A new robust method for blood vessel segmentation in retinal fundus images based on weighted line detector and hidden Markov model. Computer Methods and Programs in Biomedicine 2020; 187: 105231. doi: 10.1016/j.cmpb.2019.105231.

5. Zhang Z, Ji Z, Chen Q, et al. Joint optimization of CycleGAN and CNN classifier for detection and localization of retinal pathologies on color fundus photographs. IEEE Journal of Biomedical and Health Informatics 2021; 26(1): 115–126. doi: 10.1109/JBHI.2021.3092339.

6. Fraz MM, Barman SA, Remagnino P, et al. An approach to localize the retinal blood vessels using bit planes and centerline detection. Computer Methods and Programs in Biomedicine 2012; 108(2): 600–616. doi: 10.1016/j.cmpb.2011.08.009.

7. Asem MM, Oveisi IS, Janbozorgi M. Blood vessel segmentation in modern wide-field retinal images in the presence of additive Gaussian noise. Journal of Medical Imaging 2018; 5(3): 031405. doi: 10.1117/1.JMI.5.3.031405.

8. Thangaraj S, Periyasamy V, Balaji R. Retinal vessel segmentation using neural network. IET Image Processing 2018; 12: 669–678. doi: 10.1049/iet-ipr.2017.0284.

9. Park KB, Choi SH, Lee JY. M-GAN: Retinal blood vessel segmentation by balancing losses through stacked deep fully convolutional networks. IEEE Access 2020; 8: 146308–146322. doi: 10.1109/ACCESS.2020.3015108.

10. Yan Z, Yang X, Cheng KT. Joint segment-level and pixel-wise losses for deep learning based retinal vessel segmentation. IEEE Transactions on Biomedical Engineering 2018; 65(9): 1912–1923. doi: 10.1109/TBME.2018.2828137.

11. Mendonca AM, Campilho A. Segmentation of retinal blood vessels by combining the detection of centerlines and morphological reconstruction. IEEE Transactions on Medical Imaging 2006; 25: 1200–1213. doi: 10.1109/TMI.2006.879955.

12. Mapayi T, Owolawi PA. Retinal vascular network segmentation using adaptive thresholding method based on LSRV. In: 2020 3rd International Conference on Information and Computer Technologies (ICICT); 2020 Mar 9–12; San Jose, CA. New York: IEEE; 2020. p. 143–147.

13. Simakov SS. New boundary conditions for one-dimensional network models of hemodynamics. Computational Mathematics and Mathematical Physics 2021; 61: 2102–2117. doi: 10.1134/S0965542521120125.

14. Zhang B, Zhang L, Zhang L, Karray F. Retinal vessel extraction by matched filter with first-order derivative of Gaussian. Computers in Biology and Medicine 2010; 40: 438–445.

15. Kushol R, Kabir MH, Abdullah-Al-Wadud M, Islam MS. Retinal blood vessel segmentation from fundus image using an efficient multiscale directional representation technique Bendlets. Mathematical Biosciences and Engineering 2020; 17(6): 7751–7771. doi: 10.3934/mbe.2020394.

16. Pathan S, Kumar P, Pai R, Bhandary SV. Automated detection of optic disc contours in fundus images using decision tree classifier. Biocybernetics and Biomedical Engineering 2020; 40(1): 52–64. doi: 10.1016/j.bbe.2019.11.003.

17. Marín D, Aquino A, Gegundez-Arias ME, Bravo JM. A new supervised method for blood vessel segmentation in retinal images by using gray-level and moment invariants-based features. IEEE Transactions on Medical Imaging 2010; 30: 146–158. doi: 10.1109/TMI.2010.2064333.

18. Razban A, Mahjoory K, Nooshyar M. Segmentation of retinal blood vessels by means of 2D Gabor wavelet and fuzzy mathematical morphology. In: 2016 2nd International Conference of Signal Processing and Intelligent Systems (ICSPIS); 2016 Dec 14–15; Tehran, Iran. New York: IEEE; 2017. p. 1–5.

19. Wu H, Wang W, Zhong J, et al. SCS-Net: A scale and context sensitive network for retinal vessel segmentation. Medical Image Analysis 2021; 70: 102025. doi: 10.1016/j.media.2021.102025.




DOI: https://doi.org/10.32629/jai.v6i1.636

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Copyright (c) 2023 Mohamed Elageli M. Ghet, Omar Ismael Al-Sanjary, Ali Khatibi

License URL: https://creativecommons.org/licenses/by-nc/4.0